About HETLIOZ® (tasimelteon)

About HETLIOZ® (tasimelteon)

It may be time to ask your doctor about HETLIOZ®. If you fight to fall asleep and stay asleep at night, and struggle to stay awake during the day, you may have Non-24-Hour Sleep-Wake Disorder, also known as Non-24. Non-24 is a serious, chronic circadian rhythm disorder that affects up to 70% of people who are totally blind.

There's an FDA-approved therapy to help you improve nighttime sleep and decrease daytime sleepiness. Ask your doctor about the first and only treatment for people with Non-24, called HETLIOZ® (tasimelteon).

HETLIOZ® is the first prescription medication approved to treat Non-24.

In clinical studies, HETLIOZ® helped many people living with Non-24 sleep at night and stay awake during the day. Taken as directed by your doctor, HETLIOZ® may help you break the cycle of disrupted nighttime and unwanted daytime sleep that you've been struggling with.

The most common side effects associated with HETLIOZ® include headache, elevated liver enzymes (ALT), nightmares or abnormal dreams, and upper respiratory or urinary tract infection. These side effects may occur more frequently in patients 65 years of age or older.

HETLIOZSolutions™ was created to support people who have been diagnosed with Non-24. The program can assist with coordinating care to help answer insurance questions, as well as provide financial support and educational resources. And most importantly, by letting you know that you are not alone on this journey.

If you have questions, help is available by calling HETLIOZSolutions™ at 1-844-HETLIOZ—that's 1-844-438-5469—from 9:00AM to 8:00PM, Monday through Friday, Eastern Standard Time.

So, to get that important conversation started, here are three accessible PDFs for you to download and share with your doctor.

The first PDF can help you get the conversation with your doctor started.

Use this Doctor Discussion Guide to help you describe your symptoms to your physician, and to discuss diagnosis and potentially starting treatment with HETLIOZ®.
Download Doctor Discussion Guide

The second PDF can help you get your medication delivered.

Because HETLIOZ® is not available at retail pharmacies, there is a special process that you and your doctor will need to follow to have HETLIOZ® delivered to you. Once you have been diagnosed, and your doctor has determined that HETLIOZ® is right for you, you and your healthcare professional will need to fill out and sign the HETLIOZSolutions™ Prescription and Service Request Form.
Download Prescription and Service Request Form

This third PDF provides your doctor with information about Non-24 and HETLIOZ®.

The HETLIOZ® Guide for Your Doctor has been written specifically for doctors, and covers the science behind a circadian rhythm disorder like Non-24 as well as information about the safety and effectiveness of HETLIOZ®. So, be sure to share the information with your doctor if he or she isn't familiar with Non-24 or HETLIOZ®.

If your doctor still has questions about Non-24 and HETLIOZ®, it may be helpful to refer him or her to HETLIOZPRO.com, where we explain Non-24 and how HETLIOZ® can help.
Download HETLIOZ® Guide for Your Doctor

Here's Important Safety Information for
HETLIOZ® (tasimelteon).

Indication
HETLIOZ® is indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24).

Important Safety Information
HETLIOZ® (HeT-lee-ōz) is a prescription medication used to treat Non-24-Hour Sleep-Wake Disorder (Non-24).

HETLIOZ® may cause drowsiness. After taking HETLIOZ®, limit your activity to preparing for bed. HETLIOZ® can potentially impair your ability to perform activities that require complete mental alertness.

The most common side effects associated with HETLIOZ® include headache, elevated liver enzymes (ALT), nightmares or abnormal dreams, and upper respiratory or urinary tract infection. These side effects may occur more frequently in patients 65 years of age or older.

Tell your healthcare provider about all of the medicines you're taking. HETLIOZ® should not be taken in combination with fluvoxamine or rifampin.

Tell your healthcare provider about all of your health conditions, including whether you are pregnant, are planning to become pregnant, or are breastfeeding. HETLIOZ® has not been studied in pregnant women. HETLIOZ® should be used during pregnancy only if the potential benefit justifies the potential risks.

HETLIOZ® has not been studied in children and it is not recommended for use in patients with severe liver problems.

You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, call 1-800-FDA-1088, or report by fax at 1-800-FDA-0178.

For more information, ask your doctor or call 1-844-HETLIOZ (1-844-438-5469).

This information does not take the place of talking with your doctor for medical advice about your condition or treatment.

Download an accessible PDF or listen to the full Prescribing Information. You can also hear the full Prescribing Information by calling 1-844-HETLIOZ (1-844-438-5469).